ALL ABOUT GROWTH HORMONE

Growth hormone to be provided free in hospitals.

Growth hormone will be provided in Spanish hospitals, rather than in pharmacies, to prevent unlawful uses. Its use in healthy individuals can cause hypothyroidism, hypertension and malignant tumors cranial. Growth hormone has been considered by the Ministry of Health as a drug for hospital use, so that is not used for illicit purposes. This means that the product will be distributed in pharmacies and will be administered in health facilities. The decision, adopted by the General Directorate of Pharmacy Interterritorial Health Council, is part of the program to combat doping.

To ensure the availability of growth hormone by patients who really need it, Health and the Autonomous Communities shall establish mechanisms to facilitate the supply. In this sense, the drug may be administered in primary care centers to prevent further discomfort to the patient. The Security Committee of the Spanish Agency for Medicines and Health Products has analyzed the use of growth hormone in Spain. His conclusion is that 20% of the cases is taken without a prescription official books through theft and forgery. Doctors warn that the use of this hormone in healthy individuals can cause hypothyroidism (decreased thyroid hormone production), high head or encourage the development of malignant tumors.

A laboratory produces growth hormone from a transgenic male bovine

The objective of this initiative is to produce at lower cost and with this protein to treat dwarfism. The lab has made Argentine Bio Sidus birth of first male transgenic cattle that will be used to produce human protein hGH, also known as growth hormone. "Pampero", the name has been dubbed, is the son of "Pampa Mansa, Jersey breed calves obtained by cloning and genetically modified by the insertion of the hGH protein gene. From Pampero, the laboratory can play through traditional methods of fertilization, transgenic cows in their milk containing the aforementioned hormone for use in the treatment of pituitary dwarfism, a disorder that affects one in 1,500 children Argentina. Bio Sidus is intended to produce at lower costs and hGH protein via this method.

Currently, growth hormone is produced by culture in the laboratory, at a low volume and high production costs, to develop specific drug HHT. This means that many children with dwarfism would be dealt with, as in Argentina, for example, each dose of this drug, which should be applied daily from childhood to puberty, costs about $ 100. With the new method of production, the price of each dose should be reduced at least 50%. This is because, according to the calculations of Bio Sidus, each cow will generate five kilos per year of hormone, an amount much higher than what is produced in the laboratory. "In this model, growth hormone, present in the milk of cattle, must be isolated and purified in the laboratory to the highest homogeneity (pure protein) to develop with it an injectable medication, effective and safe," said the laboratory , which has already invested in this initiative five million dollars and plans to spend another two million to reach the production of the drug.

The U.S. FDA approves new drug treatment to help children grow with short stature

The drug was successful in patients who had not responded to regular injections of growth hormone. The FDA, the agency that regulates medicines in the United States, has just approved a new treatment to help children with short stature. "Increlex" has been developed through genetic engineering, copying the hormone IGF-1, involved in growth processes. This drug kills three decades in which he had not found any formula to eliminate the deficit in the height of children beyond the treatment based on the growth hormone produced from pituitaries of cadavers.

The drug prompted growth in children who had not responded to regular injections of growth hormone, a problem that affects a third of children with this disease. The company that has developed has been estimated at 16,000 euros the cost of therapy, a figure similar to that required with traditional growth hormone. Short stature of children not only corresponds to a deficit in the secretion of growth hormone, but also the role of this substance to induce the production of the hormone IGF-1 (insulin-like growth factor I). During aging naturally reduces the production of growth hormone and IGF-1. Therefore, pediatricians consider that at least one third of children with short stature do not have a low secretion of growth hormone but do not produce adequate levels of IGF-1.

This treatment is complementary therapies to eradicate problems of reducing the rate of growth of children aged between three and nine months old, at which time the problem can be detected. Children who are not diagnosed subsequently recorded time delays in the development of bones and teeth, as well as increased fat deposits under the skin, among other ailments. The laboratory that developed the drug application studies for type 2 diabetes, as the IGF-1, like insulin, lowers blood sugar levels. The possible development would depend on further research will have to assess public regulators of medicines.

Vegetable Proteins and growth hormones

Adequate intake of vegetables, grains and nuts can get quality protein with less saturated fat and less cholesterol than foods of animal origin. Lentils with rice, spaghetti with peas, chickpeas with pine nuts ... Obtaining proteins necessary for the proper functioning and growth of the organism can be achieved with a winning combination of plant products. Although this nutrient is identified as usual with meat, fish and eggs, the adequate in our diet of vegetables, grains or nuts of vegetable protein also takes a similar quality. This will eat less saturated fat and cholesterol, substances from foods of animal origin. The development of vegetable protein-rich food can also become an easy way to diversify the menu every day.

Proteins are essential for the formation, growth and renewal of each body cell. In fact, between 15 and 20% by weight of a healthy adult is composed of proteins. For example, different human proteins that form tissues and organs such as the keratin of skin, hair and nails, the collagen in bones, tendons and cartilage, ligaments, elastin, enzymes that allow digestion food; certain hormones such as insulin or growth hormone, and even antibodies that protect us from infections arising from the complex combination of twenty amino acids. Amino acids are the basic units of proteins and are composed of carbon, oxygen, hydrogen, nitrogen and some of them also contain sulfur.

Essential amino acids

Eight of these twenty amino acids are considered essential (essential) for the body and must be ingested through the diet because they can not get any other way. Their names are isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine, and serve to establish the quality of proteins. Thus, it contains enough of each essential amino acid called "high biological value protein or whole protein. It refers to the ability of the protein to form new ones in the individual who ingested. When the protein is deficient in one or more essential amino acids-called incomplete protein and low biological value. According to the World Health Organization, better quality protein is the egg and from it determines the biological value of protein from other foods. Our bodies need every day a certain amount of "high biological value protein, to cover the many complex roles these nutrients. The body can not synthesize human proteins if there is an essential amino acid deficiency.

Ingestion of high biological value protein food of animal origin such as eggs, meat, fish and dairy, and vegetables such as soybeans. The protein content of cereals, legumes, nuts and seeds (sesame, sunflower seeds) are deficient in some essential amino acid, which is why they are considered incomplete. Legumes and nuts are deficient in methionine and cereals and seeds are in lysine. However, as the poor are frequently different amino acid in proteins of different plants, if these foods are combined correctly, or if consumed in sufficient quantity throughout the day, and not necessarily in the same meal, "the agency get all the essential amino acids needed to produce human proteins.

The EU calls on U.S. and Canada to lift trade sanctions linked to the European ban of growth hormone-treated meat

On Tuesday came into force the new directive on the use of hormones in food, which has been tapped by the European Commission to ask the United States and Canada to lift trade sanctions imposed on the Union by the European ban on meat hormone-treated beef from both countries. According to the EU executive, the new directive will meet the requirements of the sentence imposed upon him by the World Trade Organization (WTO) by the embargo.

In 1998 the WTO ordered the European Union (EU) to ban the use of certain growth promoting hormones without a scientific analysis of the risks inherent in the consumption of meat. Since then, the EU carried out an assessment of available scientific evidence, which was used by the Council and Parliament adopted a new Community legislation. The sanctions of the United States and Canada against the Union were adopted in July 1999 and consist of an increase in customs duties on a list of certain products amounting to U.S. $ 116.8 million and 11.3 million Canadian dollars, respectively. That same year, the Commission concluded that hormone "estradiol 17th" should be avoided in the beef. As regards the other five hormones (testosterone, progesterone, trenbolone acetate, zeranol and melengestrol acetate) considered that current knowledge does not allow to provide a quantitative estimate of risk to the consumer.

New law: The new legislation confirms the prohibition of the use of hormonal substances for growth promotion of farm animals. It also reduces drastically the circumstances in which they can manage the "17th estradiol" animals for food production, for purposes other than promoting growth. As regards the other five hormones, the amended directive maintains the provisional ban to be implemented while the EU is trying to gather further scientific information to clarify the current state of knowledge on these substances.

In drafting the new directive, the EU has made a thorough analysis of risks, based on current scientific knowledge and compliance with its international obligations, said the Commissioner for Health and Consumer Protection David Byrne, for whom public health and consumer protection are "the essence of our approach to food security, based on independent scientific advice."

Successful combination of vegetarian foods

To achieve better quality of plant proteins, the suggestions are the same plate mixed in various products, compounds commonly found in traditional recipes from all continents. The variety of vegetable dishes with excellent protein quality can be as broad as the imagination allows and the desire to try new dishes.

* Legumes + grains: rice, lentils, beans or manioc paste, couscous with chickpeas and vegetables, chickpeas, wheat, peas and spaghetti with shrimp, burritos (corn bread) stuffed with beans, soybeans and rice with vegetables, chickpeas bread.
* Legumes + Nuts and seeds: chickpeas with pine nuts, walnuts lentil salad, hummus or pate chickpeas (garbanzo beans with crushed sesame seeds and spices).
* Whole-grain cereal + milk plant rice or oatmeal with soy milk shake, almonds?
* Nuts and seeds + milk plant: oats or rice with milk and nuts.
* Nuts and seeds & grains: rice salad with dried fruit, pasta with walnuts.

These combinations of vegetables are essential for all people who follow vegetarian diets. Thus they can meet their daily protein needs. Also recommended for all people because they allow for protein quality-all essential amino acids, with a lower intake of saturated fat and cholesterol, substances from foods of animal origin. Thus, continuous consumption of vegetable protein in place of the most widely consumed animal protein (primarily meat and meat products, and fish) is consistent with the criteria of a balanced diet. And if the combinations of plants sometimes included in the menus, they also serve to make more varied diet and just as nutritious and balanced, as shown in the example.

In fact, frequent and excess consumption of animal source foods is associated with an increased risk of diseases associated with excess protein, saturated fat, cholesterol and calories, such as renal failure, hyperuricemia (elevated uric acid), gout , overweight, obesity, and cardiovascular disorders such as hypercholesterolemia, hypertriglyceridemia and hypertension.

Sample menus are equivalent in quality and quantity of protein
Menu 1

* Cream of pumpkin, onion and potato
* Beef Tenderloin (120-130 g) with green peppers
* Pan and fresh fruit

Menu 2

* Salad
* Chickpeas with sautéed garlic, squash and green pepper
* Bread and rice with milk and nuts

Menu 3

* Mixed salad with walnuts
* Chickpeas with rice and sautéed garlic, squash and green pepper
* Pan and fresh fruit

Menu 4

* Rice salad with walnuts
* Saute squash, zucchini, carrot, onion, green pepper and chickpeas
* Pan and fresh fruit